WebBRGSF-A2-HIS Mouse Model. Design of the BRGSF-A2-HIS mouse. The BRGSF-A2 model is generated by inserting a human leukocyte antigen serotype A2 (HLA-A2) class I transgene in the genome of BRGSF (Balb/c Rag2 tm1Fwa IL2rγ tm1Cgn Sirpα NOD Flk2 tm1Irl) mice.These mice are subsequently used as recipients to reconstitute a functional human … Web025730 B6.129S- Rag2 tm1Fwa Cd47 tm1Fpl Il2rg tm1Wjl /J Triple Knockout mice lack RAG2, CD47, and X-linked IL2RG - making them tolerant of xenotransplantation, resistant to graft versus host disease, and susceptible to HIV. Of note, a similar strain containing a RAG1 KO, instead of a RAG2 KO, is available as Stock No. 032088 . ...
Protocol 27646 - Cd47 -Alternate 2 - The Jackson …
WebThe recombination activating gene 2 ( Rag2) interruption causes a deficiency in T and B cells. The Common gamma chain gene ( IL2RG) interruption results in a lack of functional … WebThe BRGSF-A2-HIS model is generated by inserting an human leukocyte antigen serotype A2 (HLA-A2) class I transgene in the genome of BRGSF (BALB/c Rag2 tm1Fwa Il2rg tm1Cgn Sirpa NOD Flt3 tm1lrl) mice, and subsequently reconstituted with a functional human immune system (HIS). SDRG: Immunodeficient Rat Model (→ read more) give more than a darn
Abstract 1043: Patient-derived and cell line xenograft growth in …
WebProtocol 27423: Standard PCR Assay - Rag2 Version 4. 2 Notes The genotyping protocol (s) presented here have been optimized for reagents and conditions used by The … WebProtocol 27646 - Cd47-Alternate 2 B6.129S7- Cd47 tm1Fpl /J Stock No: 003173 Protocol 27646: Standard PCR Assay - Cd47-Alternate 2 Version 1. 2 Notes The … WebNov 24, 2024 · Rag2−/− mice of both sexes were infected with Hh, of which a subgroup was followed by infection with Hp two weeks later. Co-infected males, but not females, had significantly higher total colitis index scores in the colon at both 10 and 21 weeks post-Hh infection (WPI) and developed more severe dysplasia at 21 WPI compared with mono-Hh … further redo